HTRA2 Antikörper
Kurzübersicht für HTRA2 Antikörper (ABIN7115117)
Target
Alle HTRA2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- HTRA2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- HtrA serine peptidase 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- HTRA2 (HtrA Serine Peptidase 2 (HTRA2))
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Andere Bezeichnung
- HTRA2
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Hintergrund
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Synonyms: Serine protease HTRA2, mitochondrial|High temperature requirement protein A2 (HtrA2)|Omi stress-regulated endoprotease|Serine protease 25|Serine proteinase OMI|HTRA2|OMI|PRSS25
Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
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Molekulargewicht
- 36 kDa
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Gen-ID
- 27429
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UniProt
- O43464
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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